N-Demethylclindamycin HCl CAS 22431-45-4 (free base)
| CAS No. | 22431-45-4 (free base) |
| Molecular Formula | C17H31ClN2O5S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 447.41 g/mol gives N-Demethylclindamycin HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-Demethylclindamycin HCl (CAS 22431-45-4 (free base)) is a high-purity analytical reference standard with the molecular formula C17H31ClN2O5SHCl and a molecular weight of 447.41 g/mol.
The molecular framework of N-Demethylclindamycin HCl (C17H31ClN2O5SHCl) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H31ClN2O5S HCl |
| Molecular Weight | 447.41 g/mol |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Recommended Standards
- 3,5-Bis(trifluoromethyl)pyridin-2-amine (CAS 116593-01-2)
- (2R,3R,4R,5R)-2-((benzoyloxy)methyl)-5-isothiocyanatotetrahydrofuran-3,4-diyl dibenzoate (CAS 58214-53-2)
- Benzofuro[5,6-d]isoxazole (CAS 267-57-2)
- 2,2'-(Adamantane-1,3-diyl)diacetyl chloride (CAS 31898-14-3)
- N-(3-cyano-4-((3-(trifluoromethyl)phenyl)sulfinyl)phenyl)-3-methoxybenzamide (CAS 477710-04-6)
- 2-Phenylquinoline-7-carboxylic acid (CAS 841297-69-6)
- Methyl[2-(4h-1,2,4-triazol-4-yl)ethyl]amine (CAS 1247663-92-8)
- 1-(4-hydroxy-2-pyridyl)ethanone (CAS 1196157-53-5)
- 4-(Benzyloxy)-1H-indole-7-carboxylic acid (CAS 2173992-25-9)
- Semaglutide Impurity 162 (x TFA Salt) (CAS CATO-C4X-2226162)
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